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Associate Scientist in Formulation Group

Company: Horizon Therapeutics
Location: Reston
Posted on: March 15, 2023

Job Description:

Job Description:

At Horizon Therapeutics, we define success by the number of lives touched, lives changed, and lives saved. Our global biotechnology company is made up of agile, out-of-the-box thinkers with a focus on delivering breakthrough medicines to those living with rare, autoimmune, and severe inflammatory diseases. This is the heart of our global mission. Start a career that enables you to live up to your potential and help others live up to theirs. Join us. The exceptional support we provide patients and communities equally extends to our employees. We offer industry-leading and award-winning benefits, compensation and rewards programs that positively impact all areas of our employees' personal and professional lives. Summary of Position: Horizon Therapeutics is searching for a highly motivated individual to be part of a team responsible for the development of biopharmaceutical formulations and drug product manufacturing processes. You will support our growing pipeline of medicines for patients with a wide range of rare diseases. Key responsibilities: Perform formulation screening, characterization, and stability studies to select stage-appropriate formulations of our biologic products using a variety of analytical techniques.Generate experimental protocols and documentation; perform data analysis and interpretation; report results within the department and at the cross-functional level.Conduct initial troubleshooting analysis.Support team members in writing technical reports and relevant sections of regulatory filings (e.g., INDs, IMPDs, BLAs).Assists team members with the design and transfer of robust fill-finish processes to external CMOs.Remain current on latest formulation science and strategy through the literature and conference attendance. Desired Skills and Experiences: Knowledge of protein chemistry, degradation pathways, and biophysical methods involved in characterization and formulation of proteins. Hands-on experience analyzing proteins by methods such as chromatography (e.g., SEC, IEC, RP, HIC), spectroscopy (e.g., UV-Vis) Interest to learn new analytical techniques utilized in biologics formulation development, e.g. sub-visible particle sizing techniques, capillary isoelectric focusing. Experience setting up and conducting both short-term and long-term protein stability studies. Demonstrated ability in creative problem solving and application of scientific principles. Strong verbal and written communication skills. Strong technical writing skills: preparation of protocols, reports, SOPs, etc. Attention to detail, high self-motivation and ability to set priorities. Education: Educational requirements include a degree in Biochemistry, Chemistry, Chemical Engineering or related field MS with 0-2 years experience BS with 1-3 years experience Our ValuesTransparency: We value collaboration. Trusting teach other and tackling tough challenges can make a powerful difference.Accountability: We do what's right for our patient communities through quality decisions and owning our successes and failures.Growth: We fiercely innovate and evolve to better ourselves, our communities and our patients.These three values come to life through our five Leadership Expectations that apply to all Horizon employeesEnterprise Mindset: Look beyond one's team, brand or function to see the broader company and external perspectiveExhibit Intellectual Curiosity: Seek to understand what you do not know; ask the right questions of the right people and sourcesEnsure Accountability and Courage: Step up to address difficult issues and hold self and others accountable to commitmentsEmbrace Diverse Perspectives: Welcome others with a respectful attitude; integrate diverse perspectives into ways of workingDevelop Talent: Provide feedback, coaching and mentorship to help others be more effective in their roleAt Horizon, we know that disease does not discriminate. We embrace the bold ideas of one another, foster a sense of belonging, and value inclusion. We attract and develop diverse talent because we believe that when people from different backgrounds and life experiences come together, we make lives better. Horizon intends that all qualified applications are given equal opportunity, and that selection decisions be based on job-related factors. We do not discriminate based on race, color, religion, gender, sexual orientation, national origin, age, disability, veteran status, or any other characteristics protected by law.

Keywords: Horizon Therapeutics, Reston , Associate Scientist in Formulation Group, Other , Reston, Virginia

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